Detox

Detoxification

RIAVITA Detox is a combination of extracts of herbs used in folk medicine for detoxification – silymarin from milk thistle seed, dandelion root, kombucha – and vitamin C and vitamin B complex.

10.500Ft

(30 €)

In stock

Riavita
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Detoxification, cleansing cure

By living the modern way of life, our body is exposed to countless amount of chemicals and environmental pollutants, so it is no wonder that the popularity of detoxification is rising sharply. Instead of sonorous but scientifically questionable detoxification treatments, it is much more rewarding to support the health of our main detoxifying organs, the liver and the kidneys, but bowel cleansing, lung clearing or blood vessels “unclogging” can also help our bodies.

How often and when should we hold a cleansing cure?

For a healthy person it worth to have a cleansing treatment even twice a year. This can be planned to start after a holiday, since people usually drink more alcohol on vacation than usual, which puts a burden on the liver. It is also more difficult to say no to street fast food and local specialties, and eating irregularly can upset the balance of our gut flora.

It is advisable and also recommended to have a detoxification cure after antibiotic treatment, in case of intermittent or regular medication use (e.g. acetaminophen used against the common cold slows down the cleansing function of the kidneys, thus toxins may be excreted in a decreased rate) or for those, who smoke or drink alcohol on a weekly basis. Consumption of illegal drugs is also likely to cause liver and kidney problems, as they can contain a lot of impurities or by-products with unknown effects.

For cancer patients, it is advisable to use detoxification after chemotherapy or radiation therapy, as most conventional chemotherapeutic agents, although they accumulate mostly in tumor cells, also poison the body. Many, who have undergone chemotherapy suffer from liver damage or kidney failure - the latter can also be linked to serious kidney stone disease. In this case, the only thing to look out for is to wait at least 24 hours after chemotherapy, because if you start detoxification right after treatment, you may reduce the antitumor effect of chemotherapeutic agents.

Considering the regenerative capacity of the body and liver, as well as the condition of the body, the duration of a herbal treatment is usually recommended to be 1-3 months.

The diverse role of antioxidants

When our excretory organs are under pressure, metabolism increases, thus oxidative stress elevates. Antioxidants are able to neutralize free radicals formed as a consequence of oxidative stress. Some antioxidants can also be considered a “fuel” for detoxification, for example glutathione can directly attach to the substance to be removed, facilitating its excretion. Other antioxidants help prevent liver cells from being damaged by reactive by-products formed during the breakdown of xenobiotics.

Méregtelenítés - Detox Complex
Science

Science behind

Herbs and antioxidants to support detoxification

Based on centuries of experience, folk medicine recommends such herbs for liver and kidney problems that have stood the test of time also according to today's scientific studies. The best known is the active ingredient silymarin extracted from the seeds of milk thistle, which is suitable not only as a dietary supplement, but also as a medicine, and can also help in liver diseases of various origins. Herbal use also depends on geographical location, e.g. while dandelion root has traditionally been used favorably in Europe for kidney problems, in the Far East, medicinal mushrooms like Cordyceps sinensis (caterpillar fungus) or Cordyceps militaris were applied.

3-5% of chronic renal failure results from overdosing analgesics, because of the emerging oxidative stress during the breakdown and excretion of drugs containing paracetamol or ibuprofen, which can kill kidney and liver cells.

Dandelion extract successfully counteracted elevations in liver enzymes and decreased renal disfunction in experimental rats with paracetamol overdose: fewer cells died in the kidneys, and signs of regeneration were found.

In details: Dandelion root for kidney health.

Silymarin supports the detoxifying function of liver cells. For example, the toxic compound called benzo(a)pyrene is present in small amounts in tobacco smoke or smoke-exposed grilled foods, which increases the risk of developing cancer and can also lead to nerve damage. Supported by silymarin, liver cells can neutralize the harmful effects of the compound more effectively.

  • Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity. Int J Mol Sci. 2020; 21(7):2369

 

Fatty liver is caused most often by alcohol consumption, but non-alcoholic fatty liver is also becoming more common: obese people with high cholesterol level and diabetic patients are more likely to suffer from it, which is consistent with the fact that in experimental animals, unhealthy, fat-rich food can trigger fatty liver disease. Unfortunately, some medications (certain corticosteroids, antidepressants, tamoxifen) can also cause fatty liver.

In one study, patients with non-alcoholic fatty liver disease took one of the main components of silymarin , called silibinin, and vitamin E for one year. As a result, a significant proportion of patients had decreased levels of liver enzymes related to hepatic impairment (transaminase: AST/GOT; gamma-GT) in the blood plasma, and the degree of inflammation and hepatic fibrosis associated with fatty liver was also reduced. In another 1-year-study, ALT/GPT liver enzyme levels were lowered with the combination of vitamin C and vitamin E, which also prevented the worsening of fatty liver and fibrosis in patients.

  • Silybin combined with PC and vitamin E in patients with nonalcoholic fatty liver disease. Free Radic Biol Med. 2012; 52(9):1658-65.
  • Efficiency of ursodeoxycholic acid and combination of vitamin C and E in treatment of nondiabetic nonalcoholic steatohepatitis. Georg Med News 2019; (288):81-85.

Based on laboratory and animal experiments, silymarin has been shown to inhibit the development of liver tumors (hepatocellular carcinoma) by interfering with chronic inflammatory processes and neutralizing the damaging effects of free radicals on DNA. Moreover, silibinin can improve the quality of life in patients with liver cancer treated with sorafenib. Also, based on laboratory data, polysaccharides derived from dandelion may inhibit the formation of blood vessels in the tumor.

  • Silymarin/Silybin and Chronic Liver Disease. Molecules. 2017; 22(2): 191.
  • Dandelion Polysaccharide Exerts Anti-Angiogenesis Effect on Hepatocellular Carcinoma. Front Pharm. 2020; 11:460.

Hepatitis virus infection leads to chronic liver damage. During the treatment of patients infected with hepatitis B virus, it has been observed that the use of silymarin in addition to antiviral agents (lamivudine, interferon) reduced serum levels of AST and ALT (also known as GOT and GPT) liver enzymes, and lowered the markers of hepatic fibrosis, thus the authors recommended the consumption of silymarin for Hepatitis B patients.

  • Silymarin and its combination therapy for the treatment of chronic hepatitis B. Eur J Clin Microbiol Infect Dis. 2013; 32(5):657-69.

The development of fatty liver is partly related to the condition of the intestinal flora. Through metabolic changes, the overgrowth of certain intestinal bacteria can make patients more prone to this disease. In an experiment, where mice were fed with a diet containing kombucha tea, the proportion of Lactobacilli (lactic acid bacteria) increased, and consequently, the process of fatty liver formation was hindered – as authors said. In addition, the glucuronic acid content of kombucha can also contribute to the removal of xenobiotics from the body through supporting the body's antioxidant and detoxifying systems.

  • Effect of Kombucha on gut-microbiota in mouse having non-alcoholic fatty liver disease. Food Sci Biotech. 2018; 28(1):261-267.
  • Physiological activity and expected health effects of kombucha fermented beverage. J Med Food. 2014; 17(2):179-88.

Heavy metal poisoning most often occurs due to contamination of drinking water or the soil. In this case, the micro- and macro-elements enter our body in much larger amounts than we need. Cadmium and lead are particularly toxic, but other metals can also cause severe conditions. Silymarin was able to protect human sperm cells from the heavy metal cadmium, alleviated the hepatotoxic effects of thallium and the renal damage of manganese in rats. Dandelion also protected lead-exposed rat embryos from brain damage.

  • Silymarin on cadmium-induced apoptosis in human spermatozoa. Andrologia. 2020; 52(11):e13795.
  • Protection against thallium hepatotoxicity by silymarin. J Appl Toxicol. 1988; 8(5):351-4.
  • Protective role of silymarin against manganese-induced nephrotoxicity and oxidative stress in rat. Env Tox. 2014; 29(10):1147-54.
  • Dandelion-enriched diet of mothers alleviates lead-induced damages in brain of newborn rats. Food Chem Tox. 2012; 50(7):2303-10.

Common symptoms include headache, nausea, fatigue, dry mouth, and decreased cognitive and visual abilities. Vitamin B6 is a precursor to the coenzyme pyridoxal phosphate, which accelerates the breakdown of alcohol, helps prevent the inactivation of the energy-storing ATP molecule by acetaldehyde, and plays a role in serotonin synthesis, helping to reduce hangover symptoms.

Silymarin helps to scavenge free radicals from the breakdown of alcohol that cause inflammation, thus protecting normal liver function. Dandelion extract has a similar effect: a study by Korean university students found that oxidative stress decreased and antioxidant enzyme activity increased after students consumed dandelion extract in addition to drinking 72 g of alcohol (equivalent to about 4 cans of 4.5% beer). Dandelion root extract also counteracts the kidney-damaging effects of painkillers taken against headache, which you can read more about in the "Kidney, Liver" section

  • Efficacy of metadoxine in the management of acute alcohol intoxication. J Int Med Res. 2002; 30(1):44-51.
  • Acute alcohol intoxication. Eur J Intern Med. 2008; 19(8):561-7.
  • Dietary Nutrient Intake, Alcohol Metabolism, and Hangover Severity. J Clin Med. 2019; 8(9): 1316.
  • Effect of Dandelion Juice Supplementation on Alcohol-Induced Oxidative Stress and Hangover in Healthy Male College Students. J of Korean Society of Food Sci and Nutrition. 2009; 38(6).

Detoxification

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Ingredients | Dosage

Notice

- Drink fair amount of water!
– Recommended daily dose should not be exceeded!
- Dietary supplements are not substitutes for a balanced diet.
- Dietary supplements are not medicines, nor substitutes for medicines!
- Keep out of the reach of children.

Detox összetétel
Dosage

3 capsules daily after meal in 1 or 2 portions (for example 2 capsules after breakfast and 1 after lunch).

Packaging

90 capsules

Shelf life

For 2 years from production. Expiry date is indicated on the packaging.

Storage

Avoid direct sunlight; in a dry, cool place.