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flaMemo

Flavonoids in capsules

RIAVITA flaMEMO is a special flavonoid selection with Ginkgo biloba, pine bark and green tea extracts and other herbs. In addition to flavonoids, it also contains vitamin C, vitamin B6 and selenium, all of which contribute to normal brain function. The ingredients are in titanium dioxide-free vegetable capsules.

20.500Ft

(55 €)
Riavita
info

Antioxidants for better memory

Antioxidants play an important role in keeping memory and brain functions healthy. It has been scientifically proven that people, who consume a lot of vegetables and fruits, green tea and other plant extracts, have less memory problems. In addition, the probability of cognitive decline and the risk of developing Alzheimer's disease also decrease.

And then the Flavonoids

Among plant-derived antioxidants, flavonoids play a prominent role. The beneficial effect of flavonoids on the human body was discovered by the Nobel laureate Albert Szent-Györgyi, who extracted them from red pepper and lemon juice. Their first use was to protect the blood vessels - which could also improve cognitive functions through the health of cerebral blood vessels.

Supporting all the 4 stages of memory

In the last 100 years, we learned about the mechanism of flavonoids in more details. They support the 4 main stages of the memory: efficiency of encoding, storage, recall and retrieval.

The effect is achieved through both cellular and molecular interactions. They support the cells of the vessel wall (endothelial cells), proper cerebral blood circulation and blood supply. In the hippocampus (the place where memory is stored in the brain), the creation of new neurons and the "maintenance" of existing neurons, as well as the adequacy of synaptic connections between cells, are supported by flavonoids through neurotrophic factors. The general anti-inflammatory effect of flavonoids is also involved in the protection of cognitive functions.

The brain is particularly vulnerable to oxidative stress

Our brain and nerve cells are particularly vulnerable to the damaging effects of oxidative free radicals. Our brain has a fast metabolism, it uses a lot of energy, for which it burns nutrients with the help of oxygen. During the process, many harmful free radicals are produced as a by-product of energy, which the cells neutralize with antioxidants. (Free radicals are unstable compounds that react with the biomolecules in the cells, impairing and damaging normal cell functions). Therefore, in case of an oxidative stress, which can be mental stress, intensive study, air pollution, or other influences, our brain, which already has to deal with a higher level of free radicals, has an even more difficult task.

In light of this, it is not surprising that our brain is one of our most rapidly aging organ, and one of the first signs of old age is therefore memory impairment and gradually developing dementia.

Let's consume Antioxidants!

Most vegetables and fruits are full of antioxidants. Some antioxidants are commonly found in them, others are present only in specific plants. Based on centuries-old, often millennia-old folk experiences, and confirmed by scientific results, the special flavonoids and proanthocyanidins found in the leaves of the Ginkgo biloba tree, cocoa, or the bark of the pine tree support memory and sharp thinking. Combining them with further antioxidants, a wide-range effect can be achieved.

Science

Science behind

Memory and cognitive function support by flavonoids

In the decline of cognitive functions, increased oxidative stress, inflammatory processes and damage to the brain's vasculature play an important role. In older age, the efficiency of neutralizing free radicals that mediate oxidative stress deteriorates. Besides, (mental) stress, lack of sleep, or intensive study also strain our antioxidant system in both the elderly and the young. Dietary antioxidants, chosen based on scientific data, can slow down the aging of the brain, and in some cases stimulate brain functions.

The active flavonoids and terpenes of Ginkgo biloba stimulated cerebral blood circulation, improving the brain's oxygen and nutrient supply. Based on MRI scans of 50-70-year-old men, improvement was seen for the whole brain, most significantly in the parietal and occipital white matter. Ginkgo extract directly protected neurons in a brain ischemia (stroke) model in mice. As a conclusion, it worth to support the recovery of the aging brain from neurological injuries, with natural antioxidants.

The brain is also stimulated by the extract of the maritime pine bark. According to a review study, after 3 months of regular consumption of the bark extract, alertness and attention increased, as well as episodic memory, which is part of the long-term memory system, and memory related to spatial orientation. In parallel with these processes, markers indicating oxidative stress decreased by 30%.

More and more data is being collected about the positive effects of cocoa. Summarizing the data of 366 young people under the age of 25, periodic cocoa consumption improved cerebral blood circulation and oxygen supply, and regular cocoa consumption improved cognitive performance, i.e. the processing, understanding and application of new information. The effects are largely due to the flavonoid antioxidants found in cocoa, e.g. catechin and epicatechin.

Vitamins and minerals also contribute to proper memory. One of the most important vitamins for the brain is vitamin B6, its deficiency can lead to memory disorders and dementia-like conditions. Among the minerals, selenium is the one that counteracts short-term and long-term memory disorders caused by long-term sleep deprivation in animal experiments: accumulation of oxidative stress markers were lower, when selenium was administered.

Sources:

Effects of Ginkgo biloba on cerebral blood flow assessed by quantitative MR perfusion imaging. Neuroradiology. 2011; 53(3): 185–191.

Long-term pre-treatment of antioxidant Ginkgo biloba extract EGb-761 attenuates cerebral-ischemia-induced neuronal damage in aged mice. Biomed Pharmacother. 2017; 85:256-263.

Assessing the Efficacy and Mechanisms of Pycnogenol on Cognitive Aging From In Vitro Animal and Human Studies. Front Pharmacol. 2019; 10: 694.

Effect of Cocoa Products on Cognitive Performance in Young Adults. Nutrients. 2020; 12(12): 3691.

The effect of vitamin B6 on cognition. Cochrane Database Syst Rev. 2003; (4):CD004393.

Evaluating the effect of selenium on spatial memory impairment induced by sleep deprivation. Physiol Behav. 2022; 244:113669.

Memory and learning are closely related. Based on research conducted with university students, those, who used maritime pine bark extract for 2 months, had better performance. They were able to pay attention for longer time, they remembered better to the educational material, and solved tasks more skillfully. Interestingly, their well-being also improved, they were more alert, satisfied and less anxious. They also performed better in the exams. While those who did not take the extract failed 10.7% of the tests, those who took the extract failed only 6.25%.

Daily consumption of cocoa in young adults improved cognitive performance: it was associated with more effective learning and memorization of what they heard. They also could keep their attention longer.

Sources:

Pycnogenol supplementation improves cognitive function, attention and mental performance in students. Panminerva Med. 2011; 53:75-82.

Effect of Cocoa and Cocoa Products on Cognitive Performance in Young Adults. Nutrients. 2020; 12(12): 3691.

Ginkgo biloba extract was able to alleviate the symptoms of anxiety-related mental problems, both in younger and older patients. When examining the younger age group, the condition of those suffering from generalized anxiety and adjustment disorder accompanied by depressed mood also improved significantly according to the Hamilton Anxiety Rating Scale, compared to the placebo control. The extract of the maritime pine had a mood-stabilizing and anxiety-relieving effect for professionals doing heavy mental work.

Sources:

Ginkgo biloba special extract EGb 761 in generalized anxiety disorder and adjustment disorder with anxious mood: a randomized, double-blind, placebo-controlled trial. J Psychiatr Res. 2007; 41(6):472-80.

Pycnogenol improves cognitive function, attention, mental performance and specific professional skills in healthy professionals aged 35-55. J Neurosurg Sci. 2014; 58(4):239-48.

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Ingredients | Dosage

Notice

Take it with plenty of water! Do not take more than the recommended daily dose! Dietary supplements do not replace a balanced diet. Dietary supplements are not medicines, and do not replace medicines. Keep it away from children. Do not use it during pregnancy and lactation. Due to the caffeine content, not recommended for children, and individuals with high blood pressure.

Dosage

3 capsules daily after meal.

Packaging

90 capsules

Shelf life

For 2 years from production. Expiry date is indicated on the packaging.

Storage

Avoid direct sunlight; in a dry, cool place.