RIAVITA STEMAX SL contains Chromium trace element, Shaggy Mane, Spirulina, Brown Algae Fucoidan, Sea Buckthorn extract, Ganoderma lucidum and other carefully selected herbal and fruit extracts, in titanium dioxide-free vegan capsules.
The link between cells and regeneration is currently one of the most intensively researched fields. Understanding it promises solutions that can overcome some diseases that have been considered incurable, and therefore receive more and more attention.
According to novel scientific research, the regenerative capacity of the body can be increased by stimulating and mobilizing the endogenously formed stem cells inside the body.
Stem cells can be divided into 2 main types: 1) embryonic stem cells, which have high pluripotency, so they can transform (differentiate) into almost any cell, and 2) adult or somatic stem cells, which have a lower pluripotency and are generally considered to be progenitor cells of that tissue they can be found. In terms of function, adult stem cells are responsible for the maintenance and regeneration of specific tissues, and for the replenishment of damaged and dead cells.
Stem cells are actually everywhere in our body to ensure rapid and efficient tissue regeneration. There are types of stem cells that stay in the tissues throughout, while other stem cells circulate in the body. The latter are located most of the time in the bone marrow, some of which enters the bloodstream. Then, they either return to the bone marrow or enter to the tissues from the circulation to fulfill their function.
This intra-organizational circulation is mostly the characteristic of hematopoietic stem cells (stem cells giving rise to elements of the blood and immune system), but mesenchymal stem cells (MSC, especially cartilage, fat, bone-type differentiation, but can differentiate to muscle and even neuronal direction) and endothelial progenitor cells (vascular progenitor cells) may also circulate in the blood.
Stem cells circulating in the body can enter the tissues and meet stimuli (such as damage to a particular tissue) that cause them to stay in place and differentiate into target cells. By default, only a small amount of stem cells circulate in the bloodstream, but after consuming certain plants, the number of stem cells entering the bloodstream from the bone marrow increase, which can elevate the regenerative potential.
Due to the aging process, adverse environmental effects, and unfavorable eating and lifestyle habits, the number of circulating stem cells can decrease over time, which negatively affects our body’s regeneration abilities. In such cases, the so-called stem cell mobilizers are necessary.
Type 2 diabetes is characterized by an elevated level of oxidative stress, which can be harmful for the cardiac stem cells and progenitor cells. The imbalance in the formation and regeneration of heart muscle cells can lead to cardiomyopathy, when the pump function of the heart is weakened.
Polysaccharides from astragalus successfully inhibited the damage of cardiac stem cells and progenitors in an artificial diabetic mouse model, and also enhanced the proper proliferation of these cells, thus their number increased due to the treatment. Moreover, the level of oxidative stress decreased, precluding further cellular damage.
According to a publication reviewing 25 clinical studies, chromium consumption (either alone or combined with vitamins) helped stabilizing the blood glucose level of diabetic patients. Besides, high triglyceride levels that are characteristic to diabetic conditions were also decreased in many cases.
The same conclusion was drawn, when 84 scientific publications, dated between January 2010 and December 2018, were summarized. Chromium intake improved the glycemic index, promoted cellular glucose uptake, and exerted positive effects against the complications of diabetes. The levels of triglycerides and total cholesterol were also decreasing as a result of daily chromium ingestion.
One of the potentials of uses for stimulation and mobilization of stem cells is to fight anemia, which often develops e.g. as a result of chemotherapy.
One study examined the effects of the ingredients of astragalus and angelica (ferulic acid, flavonoids, astragaloside) in mice treated with the chemotherapeutic agent cyclo-phosphamide. As a result of cyclo-phosphamide treatment, the number of red blood cells, platelets and white blood cells and the hemoglobin level drastically decreased, and the area responsible for hematopoiesis in the bone marrow shrunk. The above-listed ingredients from the herbs improved the blood count individually, however their combination improved all of the studied parameters and showed values slightly distinct from the pre-treatment condition.
Examined from a mechanistic point of view, the herbal combination (and the individual substances in varying degrees) also stimulated the self-renewal and proliferation of hematopoietic stem cells, which contributed to rapid regeneration and reversal of treatment-induced stem cell aging.
According to scientific studies, Ganoderma lucidum counteracted the detrimental effects of cyclo-phosphamide and vinerolbine chemo-therapeutic agents on the formation of blood cells in animal experiments.
Not only chemo-therapeutics, heavy metals can also harm the bone marrow. Ingesting spirulina algae helped to prevent the damage to blood cells of lead and cadmium in rats.
When the cerebral blood vessels become blocked, a state of oxygen deficiency, called ischemic stroke may occur. When the blockage is removed, fresh, oxygen-rich blood flows into the tissues, which can unfortunately often further destroy the already damaged brain cells, this is called ischemic/reperfusion injury. When a stroke occurs, the prompt intervention is very important so that neuronal death occurs in as small an area of the brain as possible.
Many herbal ingredients are known to help repair the damaged condition that develops during stroke and subsequent reperfusion. Primarily, as antioxidants, they protect neurons and tissue stem cells from reactive oxygen-radicals, which is caused by oxidative stress from re-supplying oxygen to the damaged brain area. In addition, a number of plant agents have been shown to be able to stimulate neural progenitors and neural stem cells to divide and perform neurogenesis, thus improving brain regeneration and supporting recovery.
Such herbal substances are astragalosides of astragalus root, proanthocyanidins in grape seeds, fucoidan from brown algae, but the consumption of spirulina algae or the linghzi mushroom is also a beneficial effect resulted in animal studies. The mitigation of ischemic/reperfusion damage may be supported by vitamin E, coenzyme Q10 and the rutin flavonoid, reducing the deteriorating effect of oxidative stress and pro-inflammatory cytokines.
Fucoidan can increase the regenerative capacity of the body by stimulating stem cells. In an experiment with mice, fucoidan was able to mobilize vascular wall stem cells and cardiac stem cells (scientifically known as endothelial and cardiac progenitors). Their number increased by 70% and by 25%, respectively. This elevated stem cell count helped to maintain normal vascularization of a transplanted organ, and new artery wall cells were formed to replace the dead cells in the inflamed vessel wall. The stem cell mobilizing effect of fucoidan was observed also for humans.
You can read more about the artery wall protective effect of fucoidan in the following post:
FUCOIDAN: STEM CELL MOBILIZATION AND ARTERY WALL PROTECTION
3-6 capsules daily after meal.
For 2 years from production. Expiry date is indicated on the packaging.
Avoid direct sunlight; in a dry, cool place.