As an antioxidant, Vitamin C supports the immune system in a relatively non-specific way through the balance of oxidative processes. Although the recommended minimum daily intake is 80 mg, many researchers are interested in the effect of a daily vitamin C intake of 1000 mg on various diseases.
Serum levels of both vitamin C and vitamin D are known to be inversely related to tiredness, meaning that their deficiency leads to fatigue. In a study of 62 people, participants who complained of general body pain, neck and back pain and fatigue were treated with vitamin D, and as a result, their condition began to improve rapidly.
Survivors of the stroke suffer from a high degree of fatigue and depression during the recovery phase. According to a British study, one of the reasons for this is vitamin D deficiency. All participants who received vitamin D supplementation had improved parameters. The results were also confirmed in a Chinese study of more than 500 patients recovering from an ischemic stroke.
Sources:
- Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients. 2020; 12(1): 228.
- Decrease in Serum Vitamin D Level of Older Patients with Fatigue. Nutrients. 2019; 11(10):2531.
- Vitamin D Levels in Patients Presenting with Non-Specific Neuromuscular Pain and Fatigue in Ethiopia. EJH Sci. 2020; 30(3):337-346.
- Does Vitamin D Deficiency Predispose to Post Stroke Fatigue? Ir Med J. 2020; 113(2):23.
- Effect of Vitamin D Supplementation on the Prognosis of Post-stroke Fatigue. Front Neurol. 2021; 12:690969.
It has been known since the 1940s that vitamin C deficiency can lead to high cholesterol and triglyceride levels. In severe vitamin C deficiency, cholesterol can build up in the liver to the point that it can harm the liver. In people with deficiency, taking the right amount of vitamin C has reduced blood cholesterol levels and improved cardiovascular performance.
A typical vitamin C deficiency disease is scurvy, when the walls of the capillaries become fragile and bleeding occurs. Collagen is present in the vessel wall and vitamin C is a co-factor in collagen synthesis, so if it is not present in sufficient amounts, the structure of the vessel wall will become damaged, and it can become permeable.
Source:
- Vitamin C in Disease Prevention and Cure: An Overview. Indian J Clin Biochem. 2013; 28(4): 314–328